The practice was originally founded by Dr Patrick Ryan in 1939.Dr John Ryan joined his father in the practice in 1979. He has always been interested in Primary Care Team development and was instrumental in the building of the Irishtown and Pearse St Centres and in setting up the teams.

He is a member of the Irish College of GPs, The Royal College of Physicians of Ireland and a Fellow of the Royal College of GPs in London. He has a masters degree in Medical Science and higher diplomas in Occupational Health and Dermatology. He has an ICGP certificate in Diabetes Management and the practice is part of the East Coast Diabetic Shared Care Programme.

His main interests are in Paediatrics, Diabetes and Dermatology. He is also involved in Undergraduate Education in TCD and UCD. He is a Lecturer in GP in UCD.